Signati Separo Vessel Sealing System
An investigational vessel-sealing device for vasectomy, with FDA-approved IDE for a pivotal US trial.
VasectomyA permanent outpatient procedure that blocks the vas deferens so sperm cannot enter the semen.
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Specific branded items that use this method. Compare manufacturer details, active ingredients, and regulatory status.
Clinics and telehealth services in our directory that offer this method.
Chicago Ridge, IL 60415
Urologist
Laguna Hills, CA 92653
Urologist
Midland, TX 79701
Urologist
Altamonte Springs, FL 32701
Urologist
How well it works, what to watch for, who should avoid it, and the studies behind it.
Most effective: over 99 out of 100 people successfully prevent pregnancy per year.
In the first year, failure rates are about 0.15% with typical use and 0.10% with perfect use, or 99.85% and 99.9% effective. Late failure after a semen analysis confirms no sperm is rare, roughly 1 in 2,000 cases. See the AUA Vasectomy Guideline 2026 for counseling details.
Often covered by insurance (ACA); cash-pay range roughly $450-$3,000 depending on setting (office vs. hospital), anesthesia, and location. Most in-office no-scalpel vasectomies fall between $500-$1,200; Planned Parenthood $0-$1,000 on a sliding scale.
A clinician cuts, seals, or blocks the vas deferens so sperm cannot mix with semen during ejaculation. The body absorbs the sperm, and the semen remains normal in appearance and volume.
Vasectomy is a permanent outpatient procedure that cuts, seals, or blocks the vas deferens so sperm cannot enter the semen. The body absorbs the sperm, and the semen looks and feels the same as before. Vasectomy does not affect testosterone, sex drive, erections, or ejaculation volume.
The procedure takes about 15 to 30 minutes under local anesthesia. Recovery is usually a few days with mild pain and swelling. Vasectomy is over 99.85% effective at preventing pregnancy once a follow-up semen analysis confirms no sperm, typically 8 to 12 weeks after the procedure. The number of ejaculations is not a reliable indicator of clearance.
Vasectomy is intended to be permanent. Reversal surgery (vasovasostomy) can restore sperm to the ejaculate in 71 to 97% of cases. Pregnancy rates vary by time since vasectomy: 76% for reversals within 3 years, 53% for 3 to 8 years, 44% for 9 to 14 years, and 30% for 15 or more years, per the Vasovasostomy Study Group (Belker 1992). Success also depends on the man’s age and the female partner’s age. Reversal is expensive and is usually not covered by insurance. A small percentage of men (1 to 2%) develop chronic post-vasectomy pain syndrome. Urologists or family medicine doctors trained in the procedure perform vasectomy in an in-person clinic setting.
Rest for two days after the procedure and use cold packs and supportive underwear to help reduce swelling. Avoid heavy lifting and intense exercise for one week to support healing. Discuss pain relief options with your urologist; applying cold compress pads during the first 48 hours is a simple way to ease discomfort.
Vasectomy is performed by urologists and family medicine doctors trained in the procedure, in an in-person clinic setting. Check our provider directory for vasectomy providers near you.