Compare Menopause Relief methods
Browse every side-by-side menopause relief comparison, or select methods from the list to compare your own combination.
Side-by-side comparison
| Method |  Gabapentin for Hot FlashesAn off-label gabapentin prescription that may reduce hot flashes. Pregabalin is a related gabapentinoid but is not recommended for hot flashes. | Second Method Select a method using "+ Add method" above |
|---|---|---|
| Efficacy | 45% reduction in hot flash frequency Around 45% reduction in hot flash frequency. | — |
| Cost | $4–$30 /monthly Insurance: Usually | — |
| Duration | Daily pill (ongoing) | — |
| Reversibility | Reversible | — |
| STI Protection | No | — |
| How it works | Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, which may calm overactive temperature regulation and reduce hot flash frequency. Pregabalin binds the same target but NAMS 2023 does not recommend it for hot flashes. | — |
| Prescription | Required Prescription required | — |
| Side effects |
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| Who shouldn't use this |
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