Compare Menopause Relief methods
Browse every side-by-side menopause relief comparison, or select methods from the list to compare your own combination.
Side-by-side comparison
| Method |  Phyto-SERM SupplementsPlant-based supplements with SERM-like effects that may reduce hot flashes and night sweats. A non-hormonal method. | Second Method Select a method using "+ Add method" above |
|---|---|---|
| Efficacy | Not recommended see details Not recommended by the Menopause Society. | — |
| Cost | $30–$40 /monthly Insurance: No | — |
| Duration | Daily supplement (ongoing) | — |
| Reversibility | Reversible | — |
| STI Protection | No | — |
| How it works | Phyto-SERMs are plant-derived compounds that bind to estrogen receptors and weakly modulate estrogen activity. Tissue-selective, SERM-like activity — acting in brain and bone without stimulating breast or uterine tissue — has been demonstrated only for DT56a (Femarelle), a proprietary soy-derived extract, largely in preclinical animal studies. Generic red clover and soy isoflavones are non-selective phytoestrogens. | — |
| Prescription | OTC No prescription / OTC | — |
| Side effects |
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| Who shouldn't use this |
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