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Compare Menopause Relief methods

Browse every side-by-side menopause relief comparison, or select methods from the list to compare your own combination.

Side-by-side comparison

  • Vaginal Dryness Pills SERM prescription pills that act like estrogen in some tissues and block it in others to relieve vaginal dryness and painful sex.
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Method
Vaginal Dryness Pills SERM prescription pills that act like estrogen in some tissues and block it in others to relieve vaginal dryness and painful sex.
Second method

Select a method using "+ Add method" above

EfficacyVaginal Dryness Pills Recommended

Recommended by the Menopause Society for symptom relief.

Around 68% had improvement in painful sex.

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CostVaginal Dryness Pills $35–$258 monthly Insurance: Varies—
DurationVaginal Dryness Pills Daily pill (ongoing)—
ReversibilityVaginal Dryness Pills Reversible—
STI protectionVaginal Dryness Pills No—
How it worksVaginal Dryness Pills

SERMs bind to estrogen receptors, activating estrogen pathways in some tissues and blocking them in others. Ospemifene acts like estrogen on the lining of the uterus (endometrium).

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PrescriptionVaginal Dryness Pills Required Telehealth Prescription—
Side effectsVaginal Dryness Pills
  • Hot flashes (paradoxical in some users)
  • Vaginal discharge
  • Muscle spasms
  • Hyperhidrosis
  • Headache
  • Vaginal hemorrhage
  • Night sweats
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Who shouldn't use thisVaginal Dryness Pills
  • Estrogen-dependent neoplasia
  • Active DVT, pulmonary embolism, or a history of these conditions
  • Active arterial thromboembolic disease (e.g., stroke, myocardial infarction) or a history of these conditions
  • Undiagnosed abnormal genital bleeding
  • Known or suspected pregnancy
  • Hypersensitivity to ospemifene or any ingredient
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