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Compare Menopause Relief methods

Browse every side-by-side menopause relief comparison, or select methods from the list to compare your own combination.

Side-by-side comparison

Method
Oxybutynin for Hot Flashes

Oxybutynin for Hot Flashes

An off-label anticholinergic prescription (oxybutynin) that reduces sweating and hot flashes by acting on temperature pathways.
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EfficacyRecommended (limited evidence) see details

Recommended with limited evidence by the Menopause Society.

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Cost$4–$30 /monthly

Insurance: Usually

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DurationDaily pill (ongoing)—
ReversibilityReversible—
STI ProtectionNo—
How it works

Oxybutynin blocks acetylcholine receptors in the central nervous system, which may reduce sweating and hot flashes by acting on temperature regulation pathways.

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PrescriptionRequired Prescription required—
Side effects
  • Dry mouth (over 50% of users)
  • Constipation
  • Dizziness
  • Drowsiness
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Who shouldn't use this
  • Glaucoma (narrow-angle)
  • Urinary retention
  • Gastric retention
  • Hypersensitivity to oxybutynin or any ingredient
  • Severe gastrointestinal disease (e.g., ulcerative colitis or toxic megacolon)
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