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CBT for Hot Flashes
vs
SSRIs for Hot Flashes

A side-by-side comparison of two menopause relief methods — efficacy, cost, how they work, and who shouldn't use them.

Side-by-side comparison

Method
CBT for Hot Flashes

CBT for Hot Flashes

A structured, evidence-based talk therapy that teaches skills to manage the impact of hot flashes and night sweats.

SSRIs for Hot Flashes

SSRIs for Hot Flashes

A low-dose SSRI (paroxetine 7.5 mg) approved by the FDA for moderate-to-severe hot flashes.

EfficacyRecommended see details

Recommended by the Menopause Society for symptom relief.

Recommended see details

Recommended by the Menopause Society for symptom relief.

Cost$0–$200 /per unit

Insurance: Varies

$0–$200 /monthly

Insurance: Usually

Duration4 weekly sessionsDaily pill (ongoing)
ReversibilityReversibleReversible
STI ProtectionNoNo
How it works

CBT teaches skills to manage the physical and emotional impact of hot flashes, including pacing activities, breathing techniques, and cognitive reframing. It does not eliminate hot flashes but reduces how bothersome they are.

Low-dose paroxetine affects serotonin and other neurotransmitters involved in temperature regulation, which can reduce hot flash frequency and severity.

PrescriptionOTC Therapist-delivered (no Rx)Required Prescription required
Available ProductsNo branded products yet1 product
Side effects
  • None reported in trials
  • Nausea
  • Headache
  • Fatigue or malaise
Who shouldn't use thisNone reported
  • Current or recent MAOI use (within 14 days)
  • Concomitant thioridazine or pimozide
  • Pregnancy
  • Hypersensitivity to paroxetine or any ingredient