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CBT for Hot Flashes vs SSRIs for Hot Flashes

A side-by-side comparison of two menopause relief methods — efficacy, cost, how they work, and who shouldn't use them.

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Side-by-side comparison

  • CBT for Hot Flashes A structured, evidence-based talk therapy that teaches skills to manage the impact of hot flashes and night sweats.
  • SSRIs for Hot Flashes A low-dose SSRI (paroxetine 7.5 mg) approved by the FDA for moderate-to-severe hot flashes.
Method
CBT for Hot Flashes A structured, evidence-based talk therapy that teaches skills to manage the impact of hot flashes and night sweats.
SSRIs for Hot Flashes A low-dose SSRI (paroxetine 7.5 mg) approved by the FDA for moderate-to-severe hot flashes.
EfficacyCBT for Hot Flashes Recommended

Recommended by the Menopause Society for symptom relief.

SSRIs for Hot Flashes Recommended

Recommended by the Menopause Society for symptom relief.

CostCBT for Hot Flashes $122–$227 per unit Insurance: VariesSSRIs for Hot Flashes $69–$200 monthly Insurance: Varies
DurationCBT for Hot Flashes 4 weekly sessionsSSRIs for Hot Flashes Daily pill (ongoing)
ReversibilityCBT for Hot Flashes ReversibleSSRIs for Hot Flashes Reversible
STI protectionCBT for Hot Flashes NoSSRIs for Hot Flashes No
How it worksCBT for Hot Flashes

CBT teaches skills to manage the physical and emotional impact of hot flashes, including relaxation and paced breathing, spotting and managing triggers, and cognitive strategies for unhelpful thoughts about hot flashes. It has been shown to reduce how much hot flashes bother you and interfere with daily life.

SSRIs for Hot Flashes

Low-dose paroxetine is a selective serotonin reuptake inhibitor (SSRI) that blocks the reuptake of serotonin. How it reduces hot flash frequency and severity is not known.

PrescriptionCBT for Hot Flashes Not required Professional ServiceSSRIs for Hot Flashes Required Telehealth Prescription
Side effectsCBT for Hot Flashes None reportedSSRIs for Hot Flashes
  • Nausea
  • Headache
  • Fatigue or malaise
Who shouldn't use thisCBT for Hot Flashes None reportedSSRIs for Hot Flashes
  • Current or recent MAOI use (within 14 days)
  • Concomitant thioridazine or pimozide
  • Pregnancy
  • Hypersensitivity to paroxetine or any ingredient

Key differences

The Menopause Society rates both recommended. How long it lasts: CBT for Hot Flashes, 4 weekly sessions; SSRIs for Hot Flashes, daily pill (ongoing). A prescription is needed for SSRIs for Hot Flashes, not for CBT for Hot Flashes. CBT for Hot Flashes: costs $122–$227 per unit. SSRIs for Hot Flashes: costs $69–$200 monthly.