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Clinical Hypnosis
vs
Gabapentin for Hot Flashes

A side-by-side comparison of two menopause relief methods — efficacy, cost, how they work, and who shouldn't use them.

Side-by-side comparison

Method
Clinical Hypnosis

Clinical Hypnosis

A therapist-guided technique using focused attention and suggestion to reduce hot flash frequency and severity.

Gabapentin for Hot Flashes

Gabapentin for Hot Flashes

An off-label gabapentin prescription that may reduce hot flashes. Pregabalin is a related gabapentinoid but is not recommended for hot flashes.

Efficacy80% reduction in hot flash score

Around 80% reduction in hot flash score.

45% reduction in hot flash frequency

Around 45% reduction in hot flash frequency.

Cost$100–$250 /per unit

Insurance: Varies

$4–$30 /monthly

Insurance: Usually

Duration5 weekly sessions (about 45 minutes each)Daily pill (ongoing)
ReversibilityReversibleReversible
STI ProtectionNoNo
How it works

Clinical hypnosis uses focused attention, relaxation, and suggestion to alter the perception and frequency of hot flashes. The exact mechanism is not fully understood but may involve modulation of autonomic nervous system activity.

Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, which may calm overactive temperature regulation and reduce hot flash frequency. Pregabalin binds the same target but NAMS 2023 does not recommend it for hot flashes.

PrescriptionOTC Therapist-delivered (no Rx)Required Prescription required
Available Products1 product1 product
Side effects
  • None reported in trials
  • Drowsiness
  • Dizziness
  • Fatigue
  • Headache
  • Weight gain
  • Peripheral edema
Who shouldn't use thisNone reported
  • Hypersensitivity to gabapentin or any ingredient
  • Severe renal impairment (requires dose adjustment)