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Stellate Ganglion Block
vs
Weight Loss

A side-by-side comparison of two menopause relief methods — efficacy, cost, how they work, and who shouldn't use them.

Side-by-side comparison

Method
Stellate Ganglion Block

Stellate Ganglion Block

An injection of local anesthetic into a nerve bundle in the neck that may interrupt hot flash signals for several months.

Weight Loss

Weight Loss

Losing excess weight through diet and exercise may reduce hot flashes, especially for women earlier in the menopause transition.

EfficacyRecommended (limited evidence) see details

Recommended with limited evidence by the Menopause Society.

Recommended (limited evidence) see details

Recommended with limited evidence by the Menopause Society.

Cost$500–$1,500

Insurance: No

$0–$100 /monthly

Insurance: Usually

DurationUp to 6 months per injection (based on the Walega 2014 trial endpoint)Ongoing lifestyle change
ReversibilityReversibleReversible
STI ProtectionNoNo
How it works

A clinician injects local anesthetic into the stellate ganglion, a nerve bundle in the neck that is part of the sympathetic nervous system. This may interrupt the temperature-regulation signals that trigger hot flashes.

Excess body fat may contribute to vasomotor symptoms by altering thermoregulation and hormone metabolism. Losing weight through behavioral changes (diet and exercise) may reduce the frequency and severity of hot flashes, particularly for women who are overweight or obese and earlier in the menopause transition.

PrescriptionRequired Prescription requiredOTC Therapist-delivered (no Rx)
Available ProductsNo branded products yetNo branded products yet
Side effects
  • Temporary hoarseness
  • Drooping eyelid (Horner's syndrome, temporary)
  • Nasal congestion
  • Arm weakness (temporary)
  • Rare serious complications (seizure, cardiac arrest if injected into blood vessel)
  • No physical side effects
Who shouldn't use this
  • Active anticoagulation therapy
  • Local infection at injection site
  • Severe bleeding disorder
  • Allergy to local anesthetic
  • Active eating disorder (anorexia nervosa, bulimia nervosa, or binge eating disorder)
  • Underweight or normal body weight (the evidence is for overweight or obese women)