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Pill
vs
Sponge

A side-by-side comparison of two birth control methods — efficacy, cost, how they work, and who shouldn't use them.

Side-by-side comparison

Method
Pill

Pill

No non-hormonal birth control pill is FDA-approved in the US. Ormeloxifene (centchroman) is approved and used in India.

Sponge

Sponge

A soft foam disc placed deep in the vagina before sex. It covers the cervix and contains spermicide.

EfficacyLimited evidence see details

Limited evidence: no verifiable efficacy data available.

Least effective see details

Least effective: under 90 out of 100 people successfully prevent pregnancy per year.

CostContact provider

Insurance: Varies

$15–$20 /per package

Insurance: No

DurationWeekly pill (ongoing)Single use (can be left in place up to 24 hours and for multiple acts of sex)
ReversibilityReversibleReversible
STI ProtectionNoNo
How it works

Ormeloxifene (centchroman) is a selective estrogen receptor modulator (SERM) that prevents pregnancy by inhibiting implantation of a fertilized egg in the endometrium. It does not suppress ovulation and does not contain estrogen or progestin. It is not FDA-approved in the US.

A foam disc impregnated with spermicide is placed over the cervix before sex. The spermicide kills or disables sperm and the physical barrier blocks sperm from entering the uterus.

PrescriptionRequired Prescription requiredOTC No prescription / OTC
Available Products1 product1 product
Side effects
  • Menstrual irregularities (delayed or altered periods; common, about 8-12% of users)
  • Headache
  • Nausea
  • Abdominal discomfort
  • Breast tenderness
  • Vaginal irritation or dryness
  • Increased risk of urinary tract infection
  • Rare allergic reaction
Who shouldn't use this
  • Polycystic ovarian disease (PCOS)
  • Recent history of jaundice or hepatic impairment
  • Renal impairment
  • Cervical hyperplasia or chronic cervicitis
  • Pregnancy
  • Hypersensitivity to ormeloxifene
  • Allergy to nonoxynol-9, benzalkonium chloride, or other spermicide ingredients
  • History of toxic shock syndrome
  • Active vaginal infection
  • Inability to insert or remove reliably
  • High risk of HIV exposure (frequent nonoxynol-9 use may increase vaginal irritation; CDC cautions)