Pill
vs
Vaginal pH Modulator
A side-by-side comparison of two birth control methods — efficacy, cost, how they work, and who shouldn't use them.
Side-by-side comparison
| Method |  PillNo non-hormonal birth control pill is FDA-approved in the US. Ormeloxifene (centchroman) is approved and used in India. |  Vaginal pH ModulatorA prescription gel used before sex that keeps vaginal pH acidic to disable sperm. |
|---|---|---|
| Efficacy | Limited evidence see details Limited evidence: no verifiable efficacy data available. | 86.3% typical use Least effective: under 90 out of 100 people successfully prevent pregnancy per year. |
| Cost | Contact provider Insurance: Varies | $0–$400 /per package Insurance: Usually |
| Duration | Weekly pill (ongoing) | Single use (effective for 1 hour) |
| Reversibility | Reversible | Reversible |
| STI Protection | No | No |
| How it works | Ormeloxifene (centchroman) is a selective estrogen receptor modulator (SERM) that prevents pregnancy by inhibiting implantation of a fertilized egg in the endometrium. It does not suppress ovulation and does not contain estrogen or progestin. It is not FDA-approved in the US. | A gel containing lactic acid, citric acid, and potassium bitartrate maintains an acidic vaginal pH that disables sperm and reduces their motility. It also acts as a physical barrier to sperm movement. |
| Prescription | Required Prescription required | Required Prescription required |
| Available Products | 1 product | 1 product |
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